PhD-student (f/m) in the fields of MR physics, clinical epileptology and neuroradiology Bonn University

PhD-student (f/m) job offer in Bonn/Germany

MRI SEQUENCE DEVELOPMENT FOR THE DETECTION
OF BLOOD-BRAIN BARRIER DISRUPTIONS
AND ITS IMPLEMENTATION IN CLINICAL EPILEPTOLOGY

The department of epileptology at Bonn University is looking for a PhD-student
(f/m) to join the junior research team for clinical MR-imaging led by Dr. Theodor
Rüber and supervised by Prof. Dr. Christian E. Elger. We are a multidisciplinary
research team using advanced MRI methodology to enhance our understanding and
improve diagnostics of neurological diseases with a focus on epilepsy.

Research project:

Various neurological pathologies are associated with damage to the blood-brain
barrier. MR assessment of the blood-brain-barrier is thus crucial for diagnosis and
therapy monitoring. There is first evidence showing associations of blood-brain
barrier disruptions with epilepsy and epileptic seizures. This is of utmost relevance,
as it could be used to localize the seizure onset, which in special patients may lead to
effective epilepsy surgery. The PhD-student will develop new MR sequences for
investigating the blood-brain barrier, implement them in clinical scanners and
evaluate their performance in epileptological studies. The student's successful work
will thus directly open windows for further clinical research.

Research environment:

The PhD-student will be working within a translational research project between the
fields of MR physics, clinical epileptology and neuroradiology. The work will
consequently be conducted as a cooperative project of the Bonn university hospital
department of epileptology, the German Center for Neurodegenerative Diseases
(DZNE), and the section neuroradiology of the department of radiology of the Bonn
university hospital. The thesis work will be primarily supervised by Prof. Tony
Stöcker, head of the MR physics group at the DZNE, and co-supervised by Prof. Elke
Hattingen, head of the section neuroradiology at the Bonn university hospital, and
Prof. Christian Elger, head of the Bonn department of epileptology. The shared
supervision gives the thesis a thrust in physics, yet without losing concrete clinical
perspectives.

Profile:

We are seeking a pro-active student, holding a degree in physics, computer
engineering, biology or any other STEM degree, who is as enthusiastic about
multidisciplinary research as we are and is equally interested in MR physics and in
the clinical applications of MRI. Experience in programming and excellent IT-skills
are prerequisites. As all research projects are conducted as part of the collaboration
between two research groups, we are looking for a particularly social researcher who
enjoys teamwork.
Radiologische Klinik

Offer:

Direct access to a 1.5T and 3T scanner for research.
A strong personal mentoring for career development explicitly including support in the
application for PhD-scholarships.
The cooperative integration into the research team for clinical imaging and into the
MR physics research group.
An internationally renowned neuroscience environment with a high potential for
personal development.
The opportunity to present results on national and international conferences.

Application:

The employment is in accordance with TV-L (German Salary Grade 65% TV-L 13).
The University of Bonn is an equal opportunities employer.

Please request information about the application process by sending an informal Email
to Theodor Rüber: theodor.rueber@ukbonn.de

Please refer to the application number 221_2017.
We look forward to hearing from you!

Dr. Theodor Rüber
Scientific fellow at the department of epileptology at the Bonn University Hospital

Prof. Dr. Tony Stöcker
Leader of the MR physics research group at the DZNE Bonn

Prof. Dr. Elke Hattingen
Head of the neuroradiology unit at the Bonn University Hospital

Prof. Dr. Christian E. Elger, FRCP
Head of the department of epileptology at the Bonn University Hospital


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